|
KMID : 0371619990150020249
|
|
Journal of Wonkwang Medical Science
1999 Volume.15 No. 2 p.249 ~ p.254
|
|
|
A Case of Pulmonary Histiocytosis-X Associated with Bilatera, Recurrent, and Spontaneous Pneumothorax
|
|
Song Woo-Kern
Yang Sei-Hoon
|
|
|
Abstract
|
|
|
|
Pulmonary histiocytosis X can be associated with disseminated histiocytosis X, but isolated case in the lung parenchyme is rare. Pulmonary histiocytosis X is a diffuse, smoking-related, chronic interstitial lung disease characterized by proliferation and infiltration by langerhans cell and eosinophils. The hallmark of this disorder is the electron microscopic finding of X-body or Birbeck granule that present in the lung of patient. Pulmonary histiocytosis X is common in young adult and shows variable clinical characteristics. It caused by unknown etiology. A 18 year-old man was reffered to our hospital because of pneumothorax. Plain chest X-ray and chest CT revealed thin-walled cysts of various sizes in the both lungs. Video-associated thoracoscopic lung biopsy was performed. Light microscopic examination showed proliferation and infiltration of langerhans cells. Immunohistochemically, Langerhans cells showed strong cytoplasmic staining with S-100 protein and with HLA-DR. He was treated with right pleurodesis, but pneumothorax recurred 14 days later. We reported a case of bilateral spontaneous pneumothoraces in 18 year old with pulmonary histiocytosis-X, which is confirmed by eosinophilic granuloma in Video-associated thoracoscopic lung biopsy.
|
|
|
KEYWORD
|
|
|
Pulmonary Histiocytosis X, Pneumothorax
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|